Téléchargez le livre : Drug Design of Zinc-Enzyme Inhibitors

Drug Design of Zinc-Enzyme Inhibitors

Functional, Structural, and Disease Applications

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Éditeur :

Wiley


Collection :

Wiley Series in Drug Discovery and Development

Paru le : 2009-10-22



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Description
Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes
The second most abundant transition element in living organisms, zinc spans all areas of metabolism, with zinc-containing proteins offering both established and potential drug targets. Drug Design of Zinc-Enzyme Inhibitors brings together functional and structural information relevant to these zinc-containing targets. With up-to-date overviews of the latest developments field, this unique and comprehensive text enables readers to understand zinc enzymes and evaluate them in a drug design context.
With contributions from the leaders of today's research, Drug Design of Zinc-Enzyme Inhibitors covers such key topics as:
Major drug targets like carbonic anhydrases, matrix metalloproteinases, bacterial proteases, angiotensin-converting enzyme, histone deacetylase, and APOBEC3G
Roles of recently discovered zinc-containing isozymes in cancer, obesity, epilepsy, pain management, malaria, and other conditions
Cross reactivity of zinc-enzyme inhibitors and activators
The extensive use of X-ray crystallography and QSAR studies for understanding zinc-containing proteins
Clinical applications
An essential resource for the discovery and development of new drug molecules, Drug Design of Zinc-Enzyme Inhibitors gives researchers, professionals, students, and academics the foundation to understand and work with zinc enzyme inhibitors and activators.
Pages
1040 pages
Collection
Wiley Series in Drug Discovery and Development
Parution
2009-10-22
Marque
Wiley
EAN papier
9780470275009
EAN PDF
9780470508152
Informations sur l'ebook
Nombre pages copiables
0
Nombre pages imprimables
1040
Taille du fichier
23859 Ko
Ce livre est accessible aux handicaps Voir les informations sur l'accessibilité
Prix
255,26 €

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